Ticagrelor prevents the sticking of the platelets in the blood together and inhibit the production of blood clots. It reduces the risk of death occurs due to cardiovascular diseases and myocardial infarction. Therapeutic Indication⇛ Myocardial infarction⇛ Stroke ⇛ Coronary syndrome ⇛ Stent thrombosis PharmacologyMechanism of Action:⇛ Ticagrelor couples with the G inhibitory proteins which inhibits the adenylate cyclase and further prevents the platelet aggregation.⇛ As the activation of these proteins mediates platelet aggregation and haemostasis Pharmacokinetics:Absorption: It is absorbed orallyProtein Binding: It is mainly bound to albumin and shows 99% of protein binding Metabolism: It undergoes hydroxylation and conjugation Excretion: It is excreted via urine Contraindications⇛ Contraindicated in people with known hypersensitivity⇛ Contraindicated in intracranial haemorrhage ⇛ Contraindicated in peptic ulcers Side Effects⇛ Bleeding Gums⇛ Bruising ⇛ Heavy periods ⇛ Nose bleeding Disclaimer:The data uploaded is made from content already available on internet.The company holds no right of it and is not responsible for any wrong information. |
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